diff --git a/app/controllers/ajax/anonymous_block_controller.rb b/app/controllers/ajax/anonymous_block_controller.rb
index 4e7a86f4..20503553 100644
--- a/app/controllers/ajax/anonymous_block_controller.rb
+++ b/app/controllers/ajax/anonymous_block_controller.rb
@@ -6,13 +6,15 @@ class Ajax::AnonymousBlockController < AjaxController
 
     question = Question.find(params[:question])
 
+    raise Errors::Forbidden if params[:global] && !current_user.mod?
+
     AnonymousBlock.create!(
-      user:       current_user,
+      user:       params[:global] ? nil : current_user,
       identifier: question.author_identifier,
-      question:   question
+      question:
     )
 
-    question.inboxes.first.destroy
+    question.inboxes.first&.destroy
 
     @response[:status] = :okay
     @response[:message] = t(".success")
diff --git a/app/controllers/moderation/anonymous_block_controller.rb b/app/controllers/moderation/anonymous_block_controller.rb
new file mode 100644
index 00000000..2e0ef899
--- /dev/null
+++ b/app/controllers/moderation/anonymous_block_controller.rb
@@ -0,0 +1,7 @@
+# frozen_string_literal: true
+
+class Moderation::AnonymousBlockController < ApplicationController
+  def index
+    @anonymous_blocks = AnonymousBlock.where(user: nil)
+  end
+end
diff --git a/app/javascript/retrospring/features/moderation/blockAnon.ts b/app/javascript/retrospring/features/moderation/blockAnon.ts
new file mode 100644
index 00000000..5c587300
--- /dev/null
+++ b/app/javascript/retrospring/features/moderation/blockAnon.ts
@@ -0,0 +1,46 @@
+import Rails from '@rails/ujs';
+import swal from 'sweetalert';
+
+import { showErrorNotification, showNotification } from "utilities/notifications";
+import I18n from "retrospring/i18n";
+
+export function blockAnonEventHandler(event: Event): void {
+    event.preventDefault();
+    
+    swal({
+        title: I18n.translate('frontend.mod_mute.confirm.title'),
+        text: I18n.translate('frontend.mod_mute.confirm.text'),
+        type: 'warning',
+        showCancelButton: true,
+        confirmButtonColor: "#DD6B55",
+        confirmButtonText: I18n.translate('voc.y'),
+        cancelButtonText: I18n.translate('voc.n'),
+        closeOnConfirm: true,
+    }, (dialogResult) => {
+        if (!dialogResult) {
+            return;
+        }
+
+        const sender: HTMLAnchorElement = event.target as HTMLAnchorElement;
+
+        const data = {
+            question: sender.getAttribute('data-q-id'),
+            global: 'true'
+        };
+
+        Rails.ajax({
+            url: '/ajax/block_anon',
+            type: 'POST',
+            data: new URLSearchParams(data).toString(),
+            success: (data) => {
+                if (!data.success) return false;
+
+                showNotification(data.message);
+            },
+            error: (data, status, xhr) => {
+                console.log(data, status, xhr);
+                showErrorNotification(I18n.translate('frontend.error.message'));
+            }
+        });
+    });
+}
\ No newline at end of file
diff --git a/app/javascript/retrospring/features/moderation/index.ts b/app/javascript/retrospring/features/moderation/index.ts
index 6c93249b..7d0e639a 100644
--- a/app/javascript/retrospring/features/moderation/index.ts
+++ b/app/javascript/retrospring/features/moderation/index.ts
@@ -2,11 +2,13 @@ import registerEvents from 'utilities/registerEvents';
 import { banCheckboxHandler, banFormHandler, permanentBanCheckboxHandler } from './ban';
 import { destroyReportHandler } from './destroy';
 import { privilegeCheckHandler } from './privilege';
+import { blockAnonEventHandler } from './blockAnon';
 
 export default (): void => {
   registerEvents([
-    { type: 'click', target: '[type=checkbox][name=check-your-privileges]', handler: privilegeCheckHandler, global: true },
-    { type: 'click', target: '[name=mod-delete-report]', handler: destroyReportHandler, global: true },
+    { type: 'click', target: '[type="checkbox"][name="check-your-privileges"]', handler: privilegeCheckHandler, global: true },
+    { type: 'click', target: '[name="mod-delete-report"]', handler: destroyReportHandler, global: true },
+    { type: 'click', target: '[name="mod-block-anon"]', handler: blockAnonEventHandler, global: true },
     { type: 'change', target: '[name="ban"][type="checkbox"]', handler: banCheckboxHandler, global: true },
     { type: 'change', target: '[name="permaban"][type="checkbox"]', handler: permanentBanCheckboxHandler, global: true },
     { type: 'submit', target: '#modal-ban form', handler: banFormHandler, global: true }
diff --git a/app/models/anonymous_block.rb b/app/models/anonymous_block.rb
index f5213979..accaa7e7 100644
--- a/app/models/anonymous_block.rb
+++ b/app/models/anonymous_block.rb
@@ -3,7 +3,7 @@
 require "digest"
 
 class AnonymousBlock < ApplicationRecord
-  belongs_to :user
+  belongs_to :user, optional: true
   belongs_to :question, optional: true
 
   def self.get_identifier(ip)
diff --git a/app/models/question.rb b/app/models/question.rb
index f9b8e4c3..88b5565c 100644
--- a/app/models/question.rb
+++ b/app/models/question.rb
@@ -26,4 +26,8 @@ class Question < ApplicationRecord
     return false if Inbox.where(question: self).count > 1
     true
   end
+
+  def generated? = %w[justask retrospring_exporter].include?(author_identifier)
+
+  def anonymous? = author_is_anonymous && author_identifier.present?
 end
diff --git a/app/views/answerbox/_header.haml b/app/views/answerbox/_header.haml
index 8b9277a1..1d49f545 100644
--- a/app/views/answerbox/_header.haml
+++ b/app/views/answerbox/_header.haml
@@ -18,6 +18,10 @@
                 %a.dropdown-item{ href: "#", tabindex: -1, data: { action: "ab-question-report", q_id: a.question.id } }
                   %i.fa.fa-exclamation-triangle
                   = t("voc.report")
+              - if current_user.mod? && a.question.anonymous? && !a.question.generated?
+                %a.dropdown-item{ href: "#", name: "mod-block-anon", data: { q_id: a.question.id } }
+                  %i.fa.fa-volume-off
+                  = t("voc.block_site_wide")
               - if current_user.has_role? :administrator
                 %a.dropdown-item{ href: rails_admin_path_for_resource(a.question), target: "_blank" }
                   %i.fa.fa-gears
diff --git a/app/views/inbox/_entry.haml b/app/views/inbox/_entry.haml
index 0bc31cde..dc1931e5 100644
--- a/app/views/inbox/_entry.haml
+++ b/app/views/inbox/_entry.haml
@@ -22,15 +22,18 @@
             .dropdown-menu.dropdown-menu-right{ role: :menu }
               - if i.question.user_id != current_user.id
                 %a.dropdown-item{ name: "ib-report", data: { q_id: i.question.id } }
-                  %i.fa.fa-warning
+                  %i.fa.fa-fw.fa-warning
                   = t("voc.report")
-              - if i.question.author_is_anonymous && i.question.author_identifier.present?
+              - if current_user.mod? && i.question.anonymous? && !i.question.generated?
+                %a.dropdown-item{ name: "mod-block-anon", data: { q_id: i.question.id } }
+                  %i.fa.fa-fw.fa-volume-off
+                  = t("voc.block_site_wide")
                 %a.dropdown-item{ name: "ib-block-anon", data: { q_id: i.question.id } }
-                  %i.fa.fa-minus-circle
+                  %i.fa.fa-fw.fa-minus-circle
                   = t("voc.block")
               - if current_user.has_role? :administrator
                 %a.dropdown-item{ href: rails_admin_path_for_resource(i) }
-                  %i.fa.fa-gears
+                  %i.fa.fa-fw.fa-gears
                   = t("voc.view_in_rails_admin")
   - if current_user == i.user
     .card-body
diff --git a/app/views/moderation/anonymous_block/index.haml b/app/views/moderation/anonymous_block/index.haml
new file mode 100644
index 00000000..689669f6
--- /dev/null
+++ b/app/views/moderation/anonymous_block/index.haml
@@ -0,0 +1,10 @@
+- provide(:title, generate_title(t(".title")))
+
+.container-lg.container--main
+  .card
+    .card-body
+      #entries
+        - if @anonymous_blocks.empty?
+          .text-center= t(".empty")
+        - @anonymous_blocks.each do |block|
+          = render "shared/anonymous_block", block:
diff --git a/app/views/navigation/dropdown/_profile.haml b/app/views/navigation/dropdown/_profile.haml
index 20c52295..95dfcf88 100644
--- a/app/views/navigation/dropdown/_profile.haml
+++ b/app/views/navigation/dropdown/_profile.haml
@@ -30,6 +30,9 @@
       = link_to moderation_toggle_unmask_path, method: :post, class: "dropdown-item" do
         %i.fa.fa-toggle-off
         = t(".unmask.enable")
+    %a.dropdown-item{ href: mod_anon_block_index_path }
+      %i.fa.fa-fw.fa-volume-off
+      = t(".site_wide_blocks")
     %a.dropdown-item{ href: moderation_path }
       %i.fa.fa-fw.fa-gavel
       = t(".moderation")
diff --git a/app/views/settings/blocks/index.haml b/app/views/settings/blocks/index.haml
index ab3947dc..38608e0d 100644
--- a/app/views/settings/blocks/index.haml
+++ b/app/views/settings/blocks/index.haml
@@ -22,17 +22,7 @@
     %p= t(".section.anon_blocks.body")
     %ul.list-group
       - @anonymous_blocks.each do |block|
-        %li.list-group-item
-          .d-flex
-            %div
-              - if block.question.present?
-                %p.mb-0= block.question.content
-              - else
-                %p.mb-0.text-muted.font-italic= t(".deleted_question")
-              %p.text-muted.mb-0= t(".blocked", time: time_ago_in_words(block.created_at))
-            .ml-auto.d-inline-flex
-              %button.btn.btn-default.align-self-center{ data: { action: "anon-unblock", target: block.id } }
-                %span.pe-none= t("voc.unblock")
+        = render "shared/anonymous_block", block:
 
       - if @anonymous_blocks.empty?
         %p.text-muted.text-center= t(".none")
diff --git a/app/views/shared/_anonymous_block.haml b/app/views/shared/_anonymous_block.haml
new file mode 100644
index 00000000..39cb20a9
--- /dev/null
+++ b/app/views/shared/_anonymous_block.haml
@@ -0,0 +1,11 @@
+%li.list-group-item
+  .d-flex
+    %div
+      - if block.question.present?
+        %p.mb-0= block.question.content
+      - else
+        %p.mb-0.text-muted.font-italic= t(".deleted_question")
+      %p.text-muted.mb-0= t(".blocked", time: time_ago_in_words(block.created_at))
+    .ml-auto.d-inline-flex
+      %button.btn.btn-default.align-self-center{ data: { action: "anon-unblock", target: block.id } }
+        %span.pe-none= t("voc.unblock")
\ No newline at end of file
diff --git a/config/locales/frontend.en.yml b/config/locales/frontend.en.yml
index fd1e59ee..0e734fd6 100644
--- a/config/locales/frontend.en.yml
+++ b/config/locales/frontend.en.yml
@@ -45,6 +45,10 @@ en:
       confirm:
         title: "Are you sure?"
         text: "This question will be gone forever."
+    mod_mute:
+      confirm:
+        title: "Are you sure?"
+        text: "This will mute this user for everyone."
     report:
       confirm:
         title: "Are you sure you want to report this %{type}?"
diff --git a/config/locales/views.en.yml b/config/locales/views.en.yml
index eba04ea0..66ad3f1e 100644
--- a/config/locales/views.en.yml
+++ b/config/locales/views.en.yml
@@ -305,6 +305,7 @@ en:
           heading: "Feedback"
           bugs: "Bugs"
           features: "Feature Requests"
+        site_wide_blocks: "Site-wide anonymous blocks"
     desktop:
       ask_question: "Ask a question"
       list: :user.actions.list
@@ -348,7 +349,6 @@ en:
     blocks:
       index:
         title: "Blocks"
-        blocked: "blocked %{time} ago"
         none: "You are not blocking anyone."
         section:
           blocks:
@@ -357,7 +357,6 @@ en:
           anon_blocks:
             heading: "Anonymous Blocks"
             body: "Each anonymous user you've blocked is listed here, along with a way to unblock them.  We also display the question they asked you to add some more context.  You can block anonymous users directly from the question in your inbox."
-        deleted_question: "Deleted question"
     data:
       index:
         title: "Your Data"
@@ -511,6 +510,9 @@ en:
       source: "Source code"
       terms: "Terms of Service"
       privacy: "Privacy Policy"
+    anonymous_block:
+      deleted_question: "Deleted question"
+      blocked: "blocked %{time} ago"
     sidebar:
       list:
         title: "Members"
@@ -572,6 +574,10 @@ en:
         heading: "Reason:"
         none: "No reason provided"
       view: "View reported %{content}"
+    anonymous_block:
+      index:
+        title: "Site-wide anonymous blocks"
+        empty: "There are currently no users blocked site-wide."
   user:
     actions:
       view_inbox: "View inbox"
diff --git a/config/locales/voc.en.yml b/config/locales/voc.en.yml
index 3533a892..fc15602f 100644
--- a/config/locales/voc.en.yml
+++ b/config/locales/voc.en.yml
@@ -2,6 +2,7 @@ en:
   voc:
     answer: "Answer"
     block: "Block"
+    block_site_wide: "Block user site-wide"
     cancel: "Cancel"
     close: "Close"
     confirm: "Are you sure?"
diff --git a/config/routes.rb b/config/routes.rb
index e484097a..ab4eca51 100644
--- a/config/routes.rb
+++ b/config/routes.rb
@@ -23,6 +23,7 @@ Rails.application.routes.draw do
   # Routes only accessible by moderators (moderation panel)
   authenticate :user, ->(user) { user.mod? } do
     post "/moderation/unmask", to: "moderation#toggle_unmask", as: :moderation_toggle_unmask
+    get "/moderation/blocks", to: "moderation/anonymous_block#index", as: :mod_anon_block_index
     get "/moderation(/:type)", to: "moderation#index", as: :moderation, defaults: { type: "all" }
     get "/moderation/inbox/:user", to: "moderation/inbox#index", as: :mod_inbox_index
     namespace :ajax do
diff --git a/db/migrate/20220820163035_make_user_id_on_anonymous_blocks_nullable.rb b/db/migrate/20220820163035_make_user_id_on_anonymous_blocks_nullable.rb
new file mode 100644
index 00000000..046fb385
--- /dev/null
+++ b/db/migrate/20220820163035_make_user_id_on_anonymous_blocks_nullable.rb
@@ -0,0 +1,7 @@
+# frozen_string_literal: true
+
+class MakeUserIdOnAnonymousBlocksNullable < ActiveRecord::Migration[6.1]
+  def change
+    change_column_null :anonymous_blocks, :user_id, true
+  end
+end
diff --git a/db/schema.rb b/db/schema.rb
index 140139e5..3f035379 100644
--- a/db/schema.rb
+++ b/db/schema.rb
@@ -10,7 +10,7 @@
 #
 # It's strongly recommended that you check this file into your version control system.
 
-ActiveRecord::Schema.define(version: 2022_07_20_190421) do
+ActiveRecord::Schema.define(version: 2022_08_20_163035) do
 
   # These are extensions that must be enabled in order to support this database
   enable_extension "plpgsql"
@@ -46,6 +46,8 @@ ActiveRecord::Schema.define(version: 2022_07_20_190421) do
     t.datetime "created_at"
     t.datetime "updated_at"
     t.integer "smile_count", default: 0, null: false
+    t.datetime "deleted_at"
+    t.index ["deleted_at"], name: "index_answers_on_deleted_at"
     t.index ["question_id"], name: "index_answers_on_question_id"
     t.index ["user_id", "created_at"], name: "index_answers_on_user_id_and_created_at"
   end
@@ -58,6 +60,8 @@ ActiveRecord::Schema.define(version: 2022_07_20_190421) do
     t.text "content"
     t.datetime "created_at", precision: 6, null: false
     t.datetime "updated_at", precision: 6, null: false
+    t.datetime "deleted_at"
+    t.index ["deleted_at"], name: "index_appendables_on_deleted_at"
     t.index ["parent_id", "parent_type"], name: "index_appendables_on_parent_id_and_parent_type"
     t.index ["user_id", "created_at"], name: "index_appendables_on_user_id_and_created_at"
   end
@@ -69,7 +73,9 @@ ActiveRecord::Schema.define(version: 2022_07_20_190421) do
     t.datetime "created_at"
     t.datetime "updated_at"
     t.integer "smile_count", default: 0, null: false
+    t.datetime "deleted_at"
     t.index ["answer_id"], name: "index_comments_on_answer_id"
+    t.index ["deleted_at"], name: "index_comments_on_deleted_at"
     t.index ["user_id", "created_at"], name: "index_comments_on_user_id_and_created_at"
   end
 
@@ -144,6 +150,8 @@ ActiveRecord::Schema.define(version: 2022_07_20_190421) do
     t.datetime "updated_at"
     t.integer "answer_count", default: 0, null: false
     t.boolean "direct", default: false, null: false
+    t.datetime "deleted_at"
+    t.index ["deleted_at"], name: "index_questions_on_deleted_at"
     t.index ["user_id", "created_at"], name: "index_questions_on_user_id_and_created_at"
   end
 
@@ -292,7 +300,9 @@ ActiveRecord::Schema.define(version: 2022_07_20_190421) do
     t.datetime "export_created_at"
     t.string "otp_secret_key"
     t.integer "otp_module", default: 0, null: false
+    t.datetime "deleted_at"
     t.index ["confirmation_token"], name: "index_users_on_confirmation_token", unique: true
+    t.index ["deleted_at"], name: "index_users_on_deleted_at"
     t.index ["email"], name: "index_users_on_email", unique: true
     t.index ["reset_password_token"], name: "index_users_on_reset_password_token", unique: true
     t.index ["screen_name"], name: "index_users_on_screen_name", unique: true
diff --git a/lib/use_case/question/create.rb b/lib/use_case/question/create.rb
index 7a5e0f56..7ec5b7fc 100644
--- a/lib/use_case/question/create.rb
+++ b/lib/use_case/question/create.rb
@@ -72,7 +72,7 @@ module UseCase
 
       def filtered?(question)
         target_user.mute_rules.any? { |rule| rule.applies_to? question } ||
-          (anonymous && target_user.anonymous_blocks.where(identifier: question.author_identifier).any?)
+          (anonymous && AnonymousBlock.where(identifier: question.author_identifier, user_id: [target_user.id, nil]).any?)
       end
 
       def source_user
diff --git a/spec/controllers/ajax/anonymous_block_controller_spec.rb b/spec/controllers/ajax/anonymous_block_controller_spec.rb
index 24730037..689916d8 100644
--- a/spec/controllers/ajax/anonymous_block_controller_spec.rb
+++ b/spec/controllers/ajax/anonymous_block_controller_spec.rb
@@ -13,9 +13,9 @@ describe Ajax::AnonymousBlockController, :ajax_controller, type: :controller do
         sign_in(user)
       end
 
-      context "when all parameters are given" do
+      context "when all required parameters are given" do
         let(:question) { FactoryBot.create(:question, author_identifier: "someidentifier") }
-        let!(:inbox) { FactoryBot.create(:inbox, user: user, question: question) }
+        let!(:inbox) { FactoryBot.create(:inbox, user:, question:) }
         let(:params) do
           { question: question.id }
         end
@@ -35,6 +35,51 @@ describe Ajax::AnonymousBlockController, :ajax_controller, type: :controller do
         include_examples "returns the expected response"
       end
 
+      context "when blocking a user globally" do
+        let(:question) { FactoryBot.create(:question, author_identifier: "someidentifier") }
+        let!(:inbox) { FactoryBot.create(:inbox, user:, question:) }
+        let(:params) do
+          { question: question.id, global: "true" }
+        end
+
+        context "as a moderator" do
+          let(:expected_response) do
+            {
+              "success" => true,
+              "status"  => "okay",
+              "message" => anything
+            }
+          end
+
+          before do
+            user.add_role(:moderator)
+          end
+
+          it "creates an site-wide anonymous block" do
+            expect { subject }.to(change { AnonymousBlock.count }.by(1))
+            expect(AnonymousBlock.last.user_id).to be_nil
+          end
+
+          include_examples "returns the expected response"
+        end
+
+        context "as a regular user" do
+          let(:expected_response) do
+            {
+              "success" => false,
+              "status"  => "forbidden",
+              "message" => anything
+            }
+          end
+
+          it "does not create an anonymous block" do
+            expect { subject }.not_to(change { AnonymousBlock.count })
+          end
+
+          include_examples "returns the expected response"
+        end
+      end
+
       context "when parameters are missing" do
         let(:params) { {} }
         let(:expected_response) do
diff --git a/spec/controllers/moderation/anonymous_block_controller_spec.rb b/spec/controllers/moderation/anonymous_block_controller_spec.rb
new file mode 100644
index 00000000..f2147756
--- /dev/null
+++ b/spec/controllers/moderation/anonymous_block_controller_spec.rb
@@ -0,0 +1,56 @@
+# frozen_string_literal: true
+
+require "rails_helper"
+
+describe Moderation::AnonymousBlockController, :ajax_controller, type: :controller do
+  describe "#index" do
+    subject { get :index }
+
+    shared_examples_for "should render the page successfully" do
+      it "should render the page successfully" do
+        subject
+        expect(response).to have_rendered(:index)
+        expect(response).to have_http_status(200)
+      end
+    end
+
+    shared_examples_for "empty" do
+      it "should assign an empty result set" do
+        subject
+        expect(assigns(:anonymous_blocks)).to be_empty
+      end
+    end
+
+    context "when there are no anonymous blocks" do
+      include_examples "empty"
+      include_examples "should render the page successfully"
+    end
+
+    context "when there are some anonymous blocks set" do
+      before do
+        %w[a b c].each do |identifier|
+          AnonymousBlock.create!(identifier:)
+        end
+      end
+
+      it "should assign an result set" do
+        subject
+        expect(assigns(:anonymous_blocks).length).to eq(3)
+      end
+
+      include_examples "should render the page successfully"
+    end
+
+    context "when there are only anonymous blocks assigned for users" do
+      before do
+        user = FactoryBot.create(:user)
+        %w[a b c].each do |identifier|
+          AnonymousBlock.create!(user:, identifier:)
+        end
+      end
+
+      include_examples "empty"
+      include_examples "should render the page successfully"
+    end
+  end
+end
diff --git a/spec/lib/use_case/question/create_spec.rb b/spec/lib/use_case/question/create_spec.rb
index ba7d7f23..79ae1aca 100644
--- a/spec/lib/use_case/question/create_spec.rb
+++ b/spec/lib/use_case/question/create_spec.rb
@@ -79,6 +79,18 @@ describe UseCase::Question::Create do
 
       it_behaves_like "creates the question", false
     end
+
+    context "question is from an anon who is blocked globally" do
+      before do
+        AnonymousBlock.create!(
+          identifier:  author_identifier,
+          question_id: FactoryBot.create(:question).id,
+          user_id:     nil
+        )
+      end
+
+      it_behaves_like "creates the question", false
+    end
   end
 
   context "user signed in" do